Jan C Grutters Selected Research

Sarcoidosis (Schaumann Disease)

1/2022	Predictors of appropriate implantable cardiac defibrillator therapy in cardiac sarcoidosis.
1/2022	Echocardiographic estimate of pulmonary artery pressure in sarcoidosis patients - real world data from a multi-national study.
12/2021	Activation of Downstream mTORC1 Target Ribosomal Protein S6 Kinase (S6K) Can Be Found in a Subgroup of Dutch Patients with Granulomatous Pulmonary Disease.
1/2021	Evaluating the Minimal Clinically Important Difference of the King's Sarcoidosis Questionnaire in a Multicenter Prospective Study.
1/2021	A Polymorphism in C-C Chemokine Receptor 5 (CCR5) Associates with Löfgren's Syndrome and Alters Receptor Expression as well as Functional Response.
1/2021	Presence of Propionibacterium acnes in granulomas associates with a chronic disease course in Dutch sarcoidosis patients.
1/2021	Elevated Serum Amyloid a Levels Are not Specific for Sarcoidosis but Associate with a Fibrotic Pulmonary Phenotype.
10/2020	Design of a randomized controlled trial to evaluate effectiveness of methotrexate versus prednisone as first-line treatment for pulmonary sarcoidosis: the PREDMETH study.
4/2020	Randomised, placebo-controlled trial of dexamethasone for quality of life in pulmonary sarcoidosis.
3/2020	The effects of pharmacological interventions on quality of life and fatigue in sarcoidosis: a systematic review.

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Jan C Grutters Research Topics

Disease

47	Sarcoidosis (Schaumann Disease) 01/2022 - 04/2002
22	Pneumonia (Pneumonitis) 02/2022 - 08/2008
18	Idiopathic Pulmonary Fibrosis 05/2022 - 03/2009
18	Interstitial Lung Diseases (Interstitial Lung Disease) 12/2021 - 12/2003
13	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2021 - 01/2006
10	Pulmonary Sarcoidosis 02/2022 - 12/2003
10	Lung Diseases (Lung Disease) 12/2021 - 12/2003
10	Fibrosis (Cirrhosis) 01/2021 - 06/2006
7	Inflammation (Inflammations) 02/2022 - 01/2011
7	Neoplasms (Cancer) 01/2020 - 05/2009
6	Bronchiolitis Obliterans Syndrome 01/2020 - 06/2010
5	Fatigue 01/2021 - 10/2011
5	Infections 04/2017 - 12/2012
4	Necrosis 03/2020 - 10/2015
4	Breast Neoplasms (Breast Cancer) 01/2019 - 05/2009
3	Granuloma 12/2021 - 01/2014
2	Disease Progression 05/2022 - 10/2020
2	Pulmonary Hypertension 03/2022 - 01/2022
2	Connective Tissue Diseases (Connective Tissue Disease) 12/2021 - 09/2020
2	Lung Neoplasms (Lung Cancer) 03/2021 - 01/2018
2	Osteoporosis 10/2019 - 01/2019
2	Idiopathic Interstitial Pneumonias 01/2018 - 03/2007
2	Pneumococcal Pneumonia 11/2014 - 09/2012
1	Asbestosis 05/2022
1	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 01/2022
1	COVID-19 01/2022
1	Shock 01/2022
1	Death (Near-Death Experience) 01/2022
1	Diabetes Mellitus 10/2021
1	Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) 04/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2021
1	Myositis (Idiopathic Inflammatory Myopathies) 09/2020
1	Pain (Aches) 04/2020
1	Weight Gain 01/2019
1	Hypersensitivity (Allergy) 01/2019

Drug/Important Bio-Agent (IBA)

16	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2005
10	Dexamethasone (Maxidex)FDA LinkGeneric 02/2022 - 06/2011
9	Infliximab (Remicade)FDA Link 03/2020 - 01/2013
8	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2022 - 06/2011
7	Proteins (Proteins, Gene)FDA Link 12/2021 - 12/2003
6	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2008
6	CytokinesIBA 04/2020 - 03/2003
6	Interleukin-2 Receptors (IL 2 Receptor)IBA 04/2020 - 07/2003
5	SteroidsIBA 01/2022 - 11/2008
5	Surface-Active Agents (Surfactants)IBA 03/2021 - 12/2003
5	Methotrexate (Mexate)FDA LinkGeneric 10/2020 - 09/2013
5	Prednisone (Sone)FDA LinkGeneric 10/2020 - 09/2013
5	Pharmaceutical PreparationsIBA 03/2020 - 09/2007
5	AntigensIBA 01/2020 - 05/2009
4	pirfenidoneIBA 05/2022 - 11/2014
4	CC ChemokinesIBA 01/2021 - 11/2003
4	AntibodiesIBA 09/2020 - 05/2011
4	ChemokinesIBA 04/2020 - 09/2010
4	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 04/2020 - 03/2007
4	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 01/2018 - 12/2003
3	Rituximab (Mabthera)FDA Link 01/2020 - 08/2008
3	Monoclonal AntibodiesIBA 01/2019 - 10/2015
3	Biological ProductsIBA 10/2015 - 06/2010
3	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2012 - 02/2012
3	Interleukin-6 (Interleukin 6)IBA 09/2012 - 03/2003
2	Telomerase (Telomerase Reverse Transcriptase)IBA 04/2021 - 01/2018
2	Carbon MonoxideIBA 10/2019 - 02/2006
2	Everolimus FDA Link 01/2019 - 08/2014
2	Adenosine Triphosphate (ATP)IBA 09/2018 - 12/2010
2	Protein CIBA 09/2018 - 12/2010
2	GlucocorticoidsIBA 01/2018 - 10/2015
2	nintedanibIBA 01/2018 - 11/2014
2	HLA-DRB1 Chains (HLA DRB1)IBA 01/2017 - 10/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2016 - 04/2002
2	Adalimumab (Humira)FDA Link 01/2016 - 01/2014
2	Azathioprine (Imuran)FDA LinkGeneric 09/2014 - 09/2013
2	InterleukinsIBA 02/2014 - 10/2011
2	C-Reactive ProteinIBA 12/2012 - 01/2008
2	ChitinasesIBA 01/2011 - 07/2007
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 07/2009 - 08/2008
2	NucleotidesIBA 11/2003 - 04/2002
1	potassium bromideIBA 02/2022
1	4-S-(propionic acid)sulfidocyclophosphamide (PASP)IBA 01/2022
1	DEAE-Dextran (Pulsar)IBA 01/2022
1	Sirolimus (Rapamycin)FDA Link 01/2022
1	Mechanistic Target of Rapamycin Complex 1IBA 12/2021
1	Ribosomal Protein S6 Kinases (S6 Kinase)IBA 12/2021
1	Connective Tissue Growth FactorIBA 12/2021
1	Formaldehyde (Formol)FDA Link 01/2021
1	Prostaglandins AIBA 01/2021
1	Hematoxylin (Haematoxylon)IBA 01/2021
1	Eosine Yellowish-(YS) (Eosin)IBA 01/2021
1	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2021
1	ParaffinIBA 01/2021
1	beta-cyclodextrin tetradecasulfate (CTDS)IBA 09/2020
1	AutoantibodiesIBA 09/2020
1	Immunoglobulin D (IgD)IBA 01/2020
1	Tripeptidyl-Peptidase 1IBA 12/2019
1	AutoantigensIBA 01/2019

Therapy/Procedure

26	Therapeutics 03/2022 - 01/2008
9	Lung Transplantation 01/2017 - 06/2010
5	Length of Stay 01/2022 - 06/2011
1	Defibrillators (Defibrillator) 01/2022
1	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 01/2022
1	Biological Therapy 03/2020